Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1. [4ZQK]
Targeting the PD-1/PD-L1 immunologic checkpoint with monoclonal antibodies has recently provided breakthrough progress in the treatment of melanoma, non-small cell lung cancer, and other types of cancer.
You can now get a table of the values of the potential energy of electrostatic interaction between PD-1 and PD-L1
You can order alanine scanning or mutagenesis (from 15 substitutions of amino acid residues) from 1500 EURO or a detailed study of the properties of the protein complex from 3500 Euro